Vesosomes: New Prospects in Multi Compartment Vesicular Drug Delivery System
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Author:
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KEERTHANA RAJU, GAYATHRI P.S, GAYATHRI KRISHNAKUMAR, SREEJA C NAIR
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Abstract:
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In the modern era of pharmaceutical research to improve the solubility, drug targeting, bioavailability, various drug delivery systems are discovered. To improve the efficacy and therapeutic activity these systems have advanced from micro to nano scale. Later, a need for multicompartment system arised with liposome encapsulated with drug consisting a bilayer displays high stability and retention is a promising efficient drug carrier. Vesosome is one of the systems that can improve the bioavailability of the drug, duration of action and reduces toxicity. It contain multiple vesicles that can be either multilamellar or unilamellar that are aggregated to each other forms an interior bi layer structure. Vesosomes are sub microscopic in size and dimensions are about 0.5 micron to >5 microns. This review point out various vesicular drug delivery systems and will help researchers in the area of drug delivery.
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Keyword:
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Vesicles, Vesosome, Stability.
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EOI:
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-
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DOI:
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https://doi.org/10.31838/ijpr/2020.12.01.086
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