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Spectrophotometric Evaluation of Paracetamol in Bulk and Pharmaceutical Preparations
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| Author:
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NASER ATSHAN, HUSAM S. KHALAF
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| Abstract:
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An uncomplicated, new and sensitive spectrophotometric technique for determining paracetamol was presented in this research article. The suggested technique includes the reacting Sodium nitrite (NaNO2) with hydrochloric acid to yield nitrous acid (HO-NO) and the acid reacting with paracetamol in a hydrochloric acid medium for producing orange colored product with an extreme absorbing at 431.0 nm. There haven’t any observed interferences from the typical excipients in the formulations. The technique is efficaciously engaged for the determining paracetamol in numerous medicinal formulations. The fallouts have statistically compared with gotten results based on the official technique.
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| Keyword:
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Paracetamol, Spectrophotometry, Sodium nitrite, Hydrochloric acid.
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2020.12.01.039
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| Download:
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Request For Article
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