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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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The advantages and Disadvantages of Synthesizing of Arylarsonic Acids The advantages and Disadvantages of Synthesizing f Arylarsonic Acids The advantages and Disadvantages of Synthesizing

Author: FARID YAMBYSHEV
Abstract: In recent years, an interest in research in the field of arsenicorganic compounds has increased in connection with the development of anticarcinogenic drugs. In this regard, research in the field of the synthesis of arsenic derivatives is of great theoretical and practical interest. the periodic system created by D. I. Mendeleev, is a biofunctional element. Unlike phosphorus and nitrogen, arsenic has more pronounced toxic properties. Inorganic compounds derivatives, for example, halides, oxides, sulfides and other compounds, are highly toxic. Along with this, there are low-toxic substances among the organic derivatives of pentavalent arsenic. Some of them, posses certain therapeutic properties, are used in medicine, some substances are used in the agro various industries. In recent years, an interest in research in the field of arsenicorganic compounds has increased in connection with the development of anticarcinogenic drugs. In this regard, research in the field of the synthesis of arsenic cal and practical interest. Arsenic, like its counterparts from the fifth group of the periodic system created by D. I. Mendeleev, is a biofunctional element. Unlike phosphorus and nitrogen, arsenic has more pronounced toxic properties. Inorganic compounds of trivalent arsenic, arsine AsH derivatives, for example, halides, oxides, sulfides and other compounds, are highly toxic. Along with this, there toxic substances among the organic derivatives of pentavalent arsenic. Some of them, posses certain therapeutic properties, are used in medicine, some substances are used in the agro-industrial sector, in In recent years, an interest in research in the field of arsenicorganic compounds has increased in connection with the development of anticarcinogenic drugs. In this regard, research in the field of the synthesis of arsenic Arsenic, like its counterparts from the fifth group of the periodic system created by D. I. Mendeleev, is a biofunctional element. Unlike phosphorus and nitrogen, of trivalent arsenic, arsine AsH3 and its derivatives, for example, halides, oxides, sulfides and other compounds, are highly toxic. Along with this, there toxic substances among the organic derivatives of pentavalent arsenic. Some of them, possessing industrial sector, in This article provides a brief overview of methods for the synthesis of arylarsonic acids containing a specific set of substituents in the benzene ring. The advantages and disadvantages of the synthesis methods described in the literature are analyzed. The most practical version of the synthesis of these acids has been proposed, which has been improved and recommended for This article provides a brief overview of methods for the synthesis of arylarsonic acids containing a specific set substituents in the benzene ring. The advantages and disadvantages of the synthesis methods described in This article provides a brief overview of methods for the synthesis of arylarsonic acids containing a specific set substituents in the benzene ring. The advantages and disadvantages of the synthesis methods described in the literature are analyzed. The most practical version of the synthesis of these acids has been proposed, which has been improved and recommended for use
Keyword: arsenic derivatives, phenylarsonic acid, arylarsonic acid, diazotization, arsening. INTRODUCTION The study of arylarsonic acids is important due to the fact that they are used to synthesize a wide range of arsenic-organic compounds, including primary, secondary arsine chlorides, tertiary asymmetric arsines and their derivatives, which have useful properties in terms of their biological and fungicidal activity. METHODS arsenic derivatives, phenylarsonic acid, arylarsonic acid, diazotization, arsening.
DOI: https://doi.org/10.31838/ijpr/2020.12.01.154
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