IJPR  articles are Indexed in SCOPUSClick Here     Impact Factor for Five Years is 0.13 (2013 - 2018).    

logo

INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence

IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
ISSN
0975-2366
Current Issue
Article In Press
Prevalence and Risk Factors of Occupation Induced Asthma among Traffic Police in Bangalore City
o Estimate the Prevalence of Depression, Anxiety, and Stress among Adolescents in Kancheepuram District, Tamil Nadu
A Study on Risk Factors of Anaemia among Pregnant Women
n Approach of Nutritional Deficiency Disorder among Pregnant Women
The Determinants of Self Care Practices By Using DSME to Facilitate the Patients In Kanchipuram District
An evaluation of Epidemiological Factors Relating to Overweight, Obesity in Urban Chennai
A study on the Pattern of Body Image Perception among Adolescents in Urban Chennai
mpact of an External and Internal factors of overweight and obesity in urban
A study on Anti-Rabies Vaccine among Dog Bite Victims in chennai region
Hospital Based Cross Sectional Study: Distribution of Compliance for completion of ARV 4 dose among study participants
12345678910...
ADOBE READER

(Require Adobe Acrobat Reader to open, If you don't have Adobe Acrobat Reader)

Index Page 1
Click here to Download
IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

Click to download
 

Article Detail

Label
Label
Anti-elastase of Leaves and Stem Bark Extract of Garcinia daedalanthera Pierre

Author: ENENG SILFI, BERNA ELYA , YESI DESMIATY, HANITA OMAR
Abstract: Purpose: Garcinia daedalanthera Pierre is one of the Clusiaceae family and a native plant from Sulawesi Island, in Indonesia. Elastase enzyme can reduce the elasticity of the skin, causing aging. The study aims to determine the inhibitory activity of the elastase enzyme from G. daedalanthera Pierre. Methodology: The extract was obtained by maceration successively method. The anti-elastase assay using the spectrophotometric method at 405 nm. The enzyme for the anti-elastase assay used porcine pancreatic elastase (PPE), and the substrate used N-Succ-(Ala)-3-p-nitroanilide (SANA). The phytochemical screening for the highest anti-elastase inhibition by qualitatively test. Results: The elastase inhibitory test results of 100 ppm (triplicate) showed that the leaves methanol extract was 23.38 ± 8.38 %, the leaves ethyl acetate extract was 28.91 ± 15.19 %, the leaves hexane extract was 8.14 ± 11.20 %, the stem bark methanol extract was 24.41 ± 5.32 %,and the ethyl acetate extract of stem bark was 43.96 ± 12.53 %. The result of phytochemical screening of the ethyl acetate extract of the G. daedalanthera Pierre stem bark showed that the extract contained flavonoids, alkaloids, tannins, glycoside, and anthraquinones. Applications/Originality/Value: The ethyl acetate extract of G. daedalanthera Pierre stem bark has the highest activity as anti-elastase.
Keyword: Inhibitory activity, anthraquinones, Pierre leaves
DOI: https://doi.org/10.31838/ijpr/2020.12.01.126
Download: Request For Article
 












ONLINE SUBMISSION
USER LOGIN


Username
Password
Login | Register
News & Events
0.12
2018CiteScore
 
8th percentile
Powered by  Scopus
Google Scholar

hit counters free
0.07
2017CiteScore
 
11th percentile
Powered by  Scopus