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Prevalence and Risk Factors of HBV, HCV, and HIV Infection in Thalassemia Patients Requiring Oral and Maxillofacial Care in an Iranian Sub-population
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| Author:
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EHSAN ALIABADI, SAEID TAVANAFAR
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| Abstract:
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Aim: Transfusion Transmitted viral Infections are still a significant burden in patients receiving blood products
in developing countries. This study aimed to determine the prevalence and risk factors of hepatitis B, hepatitis
C, and HIV infection in thalassemic patients approaching oral and maxillofacial department.
Materials & Methods: An analytical, retrospective cohort study in thalassemic patients with a history of
multiple transfusions was conducted, and the prevalence of hepatitis B, hepatitis C, and HIV infection and their
risk factors from demographic, behavioral, and medical aspects were assessed.
Results: A total of 202 male and female thalassemic patients with age above 19 years old were studied. The
prevalence was 1.5% for HCV, 1% for HBV, and 0.5% for HIV. Major risk factors associated with these infections
were: a history of unsafe drug injection abuse (83.3% in patients with TTI's vs. 2% in non-TTI patients), and
history of sexual relationship with multiple partners (66.7% in patients with TTI's vs. 4.6% in non-TTI patients).
Duration and frequency of transfusion was not a significant risk factor related to TTI.
Conclusion: HCV infection was more frequently identified than HBV and HIV in thalassemic patients of this
study. The present situation shows HIV to be the least prevalent infection.
Clinical significance: Thalassemia patients might be more prone to blood transfusion-transmitted viral
infections compared to the general population due to their regular blood transfusion requirements.
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| Keyword:
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AIDS, cohort study, HBV, HCV, HIV, Thalassemia
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| EOI:
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| DOI:
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https://doi.org/10.31838/ijpr/2020.12.01.119
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| Download:
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