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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Surgical Outcome of the Application of Expandable Endoprosthesis in Children: A Systematic Review and Meta-Analysis

Author: REYHANEH RAHIMI, ALI MOHAMMAD ABDORAHIM KASHA, MEHRAB TAKHTDAR
Abstract: Background and Aim: Before 1970, amputation was the treatment of choice for cancers of the extremities. Progress in imaging modalities, operational reconstruction, and pre- or postoperative chemotherapy has permitted tumor removal with adequate margins preserving the integrity of the affected bone and leading to the improvement of overall survivorship. Today, 85% of the procedures for bone and soft tissue sarcomas are by LSS compared to 15% for amputation, and the overall 5-year survival is around 60%. The aim of this study was surgical outcomes after endoprosthetic reconstruction with expandable prostheses in children. Methods: MEDLINE, PubMed, Cochrane Library, Embase, ISI, google scholar were used as electronic databases to perform a systematic literature between 2010 to 2019. A commercially available software program (Endnote X9) was used for electronic title management. Searches were performed with keywords, “expandable endoprosthesis”, “tumors”,” children”,” Surgical”, “limb length discrepancy OR LLD”. Results: A total of 101 potentially relevant titles and abstracts were found during the electronic and manual search. Finally, a total of five publications fulfilled the inclusion criteria required for this systematic review. At the last follow-up, the average LLD was 34.48 mm. The functional score was excellent in 29 patients, good in 34, fair in 11, and poor in five. Infection was the most prevalent complication 14.92% of the total 106 patients. 36 soft tissue contractures were recorded in 106 patients. Conclusions: The survival rate of expandable endoprosthesis in children was 83.46%
Keyword: expandable endoprosthesis, children, limb length discrepancy
DOI: https://doi.org/10.31838/ijpr/2020.12.01.118
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