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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
ISSN
0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Antibacterial Activity of Ten Plant Extracts against Methicillin Resistant Staphylococcus aureus (MRSA)

Author: RATNA YULIANI, ANNISA DIYAN MEITASARI, DAN ROKHMATUL MALA
Abstract: Methicillin resistant Staphylococcus aureus (MRSA) is a bacterium that is resistant to many antibiotics that are widely used. This resulted in fewer drug choices for treating infections caused by MRSA. This research was conducted to test the antibacterial activity of ethanol extracts of longan leaves, cherry leaves, eucalyptus leaves, avocado leaves, bay leaves, guava leaves, mint leaves, lemongrass leaves, ginger rhizome, and banana midrib against MRSA. The powder was extracted by maceration method using ethanol 96%. The extract antibacterial activity test was carried out by disk diffusion method. Antibacterial activity test results showed that the extracts can inhibit MRSA growth except ones of guava leaves and Ambon banana midrib. Extracts that have antibacterial activity produce inhibition zone diameters around the disk of 8.3 to 17 mm. Longan leaf extract has the highest anti-MRSA activity with inhibition zone diameter of 17 mm. This indicates that longan leaves have the potential to be developed as an antibacterial agent against MRSA.
Keyword: antibacterial, extract, Methicillin resistant Staphylococcus aureus
DOI: https://doi.org/10.31838/ijpr/2020.12.01.112
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