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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
ISSN
0975-2366
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Prevalence and Risk Factors of Occupation Induced Asthma among Traffic Police in Bangalore City
To Estimate the Prevalence of Depression, Anxiety, and Stress among Adolescents in Kancheepuram District, Tamil Nadu
A Study on Risk Factors of Anaemia among Pregnant Women
An Approach of Nutritional Deficiency Disorder among Pregnant Women
The Determinants of Self Care Practices By Using DSME to Facilitate the Patients In Kanchipuram District
An evaluation of Epidemiological Factors Relating to Overweight, Obesity in Urban Chennai
A study on the Pattern of Body Image Perception among Adolescents in Urban Chennai
Impact of an External and Internal factors of overweight and obesity in urban
A study on Anti-Rabies Vaccine among Dog Bite Victims in chennai region
Hospital Based Cross Sectional Study: Distribution of Compliance for completion of ARV 4 dose among study participants
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Diabetic Nephropathy: A Review of Pathophysiological mechanisms, Therapeutic interventions and Biomarkers

Author: REEMA MITRA, PRADEEP GOYAL
Abstract: Among the three microvascular complications of diabetes (nephropathy, retinopathy and neuropathy), diabetic nephropathy is a major cause of kidney failures. This review gives an insight into all the pathways and mechanisms which have been implicated in causing kidney damage due to diabetes. Both metabolic and haemodynamic factors play a role in the disease. Various mechanisms like activation of protein kinase C, polyol pathway, etc lead to nephropathy. The review also summarises some of the newer therapeutic options for the treatment of the disease.
Keyword: Diabetic nephropathy, pathophysiological mechanisms, therapeutic options
DOI: https://doi.org/10.31838/ijpr/2020.12.01.083
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