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Synthesis and characterization of some heterocyclic compounds derivative of some chalconeswith Evaluation for Antibacterial Activity for Some of them.
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| Author:
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DHAMER. M, AYAD. SULAIMAN., IBTISAM .KHALIFA.
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| Abstract:
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Quinoxalines subsidiaries combination of Benzene-1,2-diamine was responded with oxalic corrosive to shape
1,4,4a,8a-tetrahydroquinoxaline-2,3-dion was chlorinated by utilizing Phosphorous oxytrichloride in (dmf), to frame 2,
3-dichloro-4a,8a-dihydroquinoxaline. This dichloro-4a,8a-dihydroquinoxaline compound exposed to response with 4
amino acetophenone in DMF and sodium carbonate(anhydrous) "reflexes, for 5 (h) to frame" 1-(4(3chloroquinoxalin,-2-yl)
amino)
ethanan-1-one.
Additionally
"1(3-chloroquinoxalin-2-yl),
amino)phenyl)
ethanan-1-one"
at
that
point
responded
with
relating
fragrant
aldehydes
to
frame
quinoxalinechalcone
by
claisen
Schmidt
response.
At
that
point response this quinoxalinechalcone with (hydrazine hydrate, phenyl hydrazine , thiourea , urea ,
thiosemicarbazide ) readiness quinoxalinechalcone subordinates. Every one of the mixes were described by IR, 1H
NMR
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| Keyword:
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Quinoxaline, dimethyl foramide (DMF), IR, 1H NMR, chalcone,
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2020.12.01.057
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| Download:
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Request For Article
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