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Assessment of Serum Interleukin-6 and Leptin Levels in Postmenopausal Iraqi Women
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| Author:
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MAHDI H.HUMMADI, HIBA S.AHMED, ZAINABS.HUSSIEN, ZINAHS.ALI
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| Abstract:
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Menopause is the perpetual termination of menstruation owed to defeat of ovarian follicular activity. Menopause in
women leads to various physiological changes in the body. To evaluate serum interleukin-6 and leptin levels in
postmenopausal women and equated them with premenopausal women. Forty five postmenopausal women were
participated in this work and compared them with 45 premenopausal women who had a regular menstruation. They
were attending the Medical City Hospital/Obstetrics and Gynecology Department during the period from March 2019
until the end of August2019. Anthropometric and clinical parameters were taken for all individuals. In this study, there
was a significant increase
(p =0.05
)in fasting serum glucose, serum total cholesterol, triacylglycerol, low density
lipoprotein cholesterol, and leptinin postmenopausal group as paralleled to premenopausal group. There was a
decrease in serum estradiol in postmenopausal women as paralleled to premenopausal women, but it was not
significant. Additionally, there was a substantialreduction in serum progesterone while, there was a significant rise in
serum interleukin-6 in postmenopausal women as paralleled to premenopausal women. This work shows the changes
of estradiol, progesterone, and leptin levels in the postmenopausal women. Additionally, an elevation in IL6 level due
to the presence of inflammation in those women
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| Keyword:
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Postmenopause, Interleukin-6, Leptin
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2020.12.01.054
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| Download:
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Request For Article
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