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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
ISSN
0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Antibacterial evaluation of some new benzimidazole derivatives

Author: MUHANNED MAHMOUD, SURA K. IBRAHIM, MUAYAD AHMED RDAIAAN
Abstract: In this study, we synthesized a sequence of benzimidazole compounds containing. 1,3,4-thiadiazole ring and azo moiety from many reaction steps. The obtained benzimidazole series had been categorized by their melting point, FT-IR and H- NMR data and exhibited good pharmacological activities upon in vitro screening for the antibacterial activitiesin contrast to strains of selection of pathogenic Gram-positive bacteria 1 (S. aureus and B. subtilis ) and Gram- negative bacteria (E.coliand p. aeruginosa )in comparison with (Amoxicillin ) and (Ciprofloxacin ) as standard antibacterial agents
Keyword: benzimidazole ,1,3,4-thiadiazole,azo derivatives, antibacterial activity
DOI: https://doi.org/10.31838/ijpr/2020.12.01.050
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0.12
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