Antibacterial evaluation of some new benzimidazole derivatives
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Author:
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MUHANNED MAHMOUD, SURA K. IBRAHIM, MUAYAD AHMED RDAIAAN
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Abstract:
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In this study, we synthesized a sequence of benzimidazole compounds containing. 1,3,4-thiadiazole ring and azo
moiety from many reaction steps. The obtained benzimidazole series had been categorized by their melting point,
FT-IR and
H- NMR data and exhibited good pharmacological activities upon in vitro screening for the antibacterial
activitiesin contrast to strains of selection of pathogenic Gram-positive bacteria
1
(S. aureus and B. subtilis
) and Gram-
negative bacteria
(E.coliand p. aeruginosa
)in comparison with
(Amoxicillin
) and
(Ciprofloxacin
) as standard
antibacterial agents
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Keyword:
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benzimidazole ,1,3,4-thiadiazole,azo derivatives, antibacterial activity
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EOI:
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-
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DOI:
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https://doi.org/10.31838/ijpr/2020.12.01.050
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