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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Correlate the clinical response of drugs with the invitro antifungal susceptibility

Author: RISWANA M, SHABEEBA KULAH
Abstract: The emerging resistance to the common antifungal agents poses difficulty in the treatment of these conditions. Though topical antifungal therapy have good efficacy in treating most superficial fungal infections, severe infections and clinical types like Tineacapitis, Tineaunguium requires systemic therapy.In order to prophesy the therapeutic outcome of a given antimycotic agent used in the treatment of dermatophytosis, resolve of the invitrodefenselessness of the drugs may prove cooperative. With dermatophytes, a good connectionamong the invitro data and clinical outcome has beenestablished for the microdilution test and discdiffusion method.In vivo, confrontation is also connected with antifungal misuse since patients often fail to appearance the full course of treatment. An emerging resistance pattern is seen due to the misuse, inadequate and irregular course of treatment that leads to hard to treat fungal infections because of the failure to eliminate the organism completely.Therefore, evaluating the resistance pattern of the drugs is considered essential. Considering the socioeconomic conditions of our country, the need for a simple and reproducible technique of testing the invitro antifungal susceptibility has to be standardized
Keyword: dermatophytosis,invitro antifungal,like Tineacapitis, Tineaunguium and antimycotic agent
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