|
An observation for any side effects of PRP in patients with chronic diabetic foot ulcers
|
|
| Author:
|
MADHUMITHA M, SUNDARAMORTHY SRINIVASAN
|
| Abstract:
|
Among the list of ten nations with most cases of Diabetes mellitus, India is ranked in the first place with a
prevalence of 42 million cases. Foot ulceration is one of the furthermost serious and dreaded difficulties in patients
with diabetes mellitus. It contributes as one of the major reason of mortality in diabetic patients and is accountable
for prolonged periods of hospital stay. About 15% of the patients with diabetes mellitus develops foot ulcer[49]
and 85% of diabetic patients who undergo lower limb elimination have a previous foot ulcer. The annual
occurrence of diabetic foot ulcer is predictable to be 2 to 3%.There are two important functions of foot. They
support the body weight as well as act as a lever to propel the body during walking and running. The foot is
composed of many small bones so that it can adapt itself while walking on uneven surfaces, rather than being made
of single bone which makes it harder to walk on such surfaces.Several risk factors act together and lead to
formation of foot in diabetes patients. It can be approximatelyseparated into local factors and general or systemic
factors. The general factors include poor glycemic control, period of diabetes, peripheral vascular disease, chronic
renal disease, visual loss or blindness and old age. The local factors are peripheral neuropathy, anatomic foot
deformity, trauma, improperly fitted shoes, history of foot ulceration or lower limb amputation in the past, edema,
callus, imperfect joint mobility and abnormal foot pressures. There is a triad of neuropathy, trauma and deformity
seen in about two thirds of the diabetic foot ulcer patients. The other risk factors are dry or fissured skin, toe-web
tinea and onychomycosis. In some studies there are sexual differences and ethnic factors. The international
agreement on the diabetic foot devised a foot risk criteria with increasing risk for foot ulceration by categorizing
foot risk. Patients who have no neuropathy and no history of foot ulcer in the past are said to be low risk patients.
|
| Keyword:
|
deformity, trauma, improperly fitted shoes, foot ulcer,glycemic control,fissured skin, toe-web tinea and onychomycosis
|
| EOI:
|
-
|
| DOI:
|
-
|
| Download:
|
Request For Article
|
|
|