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Contribution of the antiradical mechanism to the total antioxidant activity of heterocyclic compounds
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| Author:
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S.S. ZYKOVA, S.V. PONOSOV
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| Abstract:
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The contribution of the antiradical mechanism to the total antioxidant activity of various heterocyclic
compounds is studied. It was found that the predominance of the antiradical mechanism in antioxidant activity
is largely determined by the presence of a
group and a methoxy group in the composition of a phenyl radical substituent. Analysis of the correlation of
growth of Escherichia coli M 17 in the medium with H
these substances showed that benzoxazines did not show the antioxidant activity. High prooxidant activity was
found in benzoxazines having methyl or tert
binding activity, but unlike phenacylpyrroles, benzoxazines practically showed only prooxidant activity, since
the protective effect of the compounds was not observed under the action of H
culture. In addition, the study showed that the combina
chemical compounds allows to specify their antioxidant/prooxidant effects.
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| Keyword:
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antiradical activity, antioxidant activity, correlation, benzoxazines.
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2019.11.04.097
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| Download:
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