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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence

IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

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0975-2366
5 - Years Impact Factor

Year 2012 - 2016

Impact Factor: 1.55

Total Publications: 317

Total Citation: 491

Year 2011 - 2015

Impact Factor: 1.46

Total Publications: 326

Total Citation: 477

Year 2010 - 2014

Impact Factor: 1.3

Total Publications: 313

Total Citation: 407

Year 2009 - 2013

Impact Factor: 0.973

Total Publications: 293

Total Citation: 285

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A Review on Anxiety and Its Current Drug Treatment

Author: RITIKA SHARMA, DR. PRADEEP GOYAL
Abstract: Anxiety, stress and tension are absolutely habitual human feelings. Persistence of these feelings for a longer period will affects physical and mental health both. It is considered to be the major cause of disability in world. It comprises of post-traumatic stress disorder, obsessive compulsive disorder, generalized anxiety disorder, panic attacks, phobias as well as depression. The neurotransmitters involved in brain involves in anxiety include GABA, serotonin, nor-epinephrine and dopamine. The developed ethological animal models (behavioural) demonstrated the anxiolytic properties of neurotransmitters, with the help of various models neuropeptide receptor agonist and antagonists, the potency in human clinical samples has concluded. Anti-anxiety medicines are used to treat anxiety. These medicines act by decreasing brain activity to mitigate the symptoms of anxiety, apprehensiveness and improving sleep. Prolonged use of these agents can cause serious side-effects such as cholinergic symptoms, weight gain, paradoxil effects, disturbed sleep etc. Thus, urgent need for new antianxiety drugs is a global concern. Thus, the insistence of herbal medicines is expanding due to their immense role and therapeutic efficacy with minimum side effects.
Keyword: Neurotransmitters, Serotonin, Anxiety, Anxiolytic plants.
DOI: https://doi.org/10.31838/ijpr/2019.11.04.086
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