IJPR  articles are Indexed in SCOPUSClick Here     Impact Factor for Five Years is 0.13 (2013 - 2018).    

logo

INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence

IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

ISSN
0975-2366
5 - Years Impact Factor

Year 2012 - 2016

Impact Factor: 1.55

Total Publications: 317

Total Citation: 491

Year 2011 - 2015

Impact Factor: 1.46

Total Publications: 326

Total Citation: 477

Year 2010 - 2014

Impact Factor: 1.3

Total Publications: 313

Total Citation: 407

Year 2009 - 2013

Impact Factor: 0.973

Total Publications: 293

Total Citation: 285

Current Issue
22nd NATIONAL CONVENTION

22nd National Convention of Society of Pharmacognosy & International Conference. For more details visit


For More Detail Visit ncsp.ganpatuniversity.ac.in
Article In Press
No Data found.
ADOBE READER

(Require Adobe Acrobat Reader to open, If you don't have Adobe Acrobat Reader)

Index Page 1
Click here to Download
IJPRT ISSUE

January - March 6 [1] 2014

Click to download
IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

Click to download
 

Article Detail

Label
Label
Development and Validation of Bendmustine Hydrochloride for Injection and Studies of Degradation By Using Reverse Phase Liquid chromatography

Author: SRIDHAR J.V.S, LAVKUMAR UPALLA, ANDREWS B. S. A, V.D.N. KUMAR ABBARAJU, NAGARAJU DASARI
Abstract: A validated HPLC method was developed for the determination of Bendmustine(BND) Hydrochloride (BND) in pharmaceutical formulation. Isocratic elution at a flow rate of 1.0 ml/min was employed on Symmetry shield RP18, 250mm x 4.6mm, 5µm or Equivalent. A mixture Buffer : Acetonitrile 58:42v/v were prepared and used as mobile phase. The UV detection wavelength was 233nm and 20µl sample was injected. The run time is About 15 minutes for Sample, Unmarked, Placebo, System suitability, Sensitivity solution and 60minutes for diluted Regular. The Approximate retention time was founded for BND is ± 2.4 minutes. The% R.S.D BND was identified. The mean Percentage recovery for Gemcitabine is found within the specification limit. The method was validated as per the ICH guidelines. Thus, the proposed HPLC method can be successfully applied for the routine quality control analysis of formulations. The method developed is simple and is better than the methods reported in the literature.
Keyword: RP-HPLC Refractive index detector, BND, flow rate, column, ICH Guidelines, USP reference.
DOI: https://doi.org/10.31838/ijpr/2019.11.04.084
Download: Request For Article
 












ONLINE SUBMISSION
USER LOGIN


Username
Password
Login | Register
Pharmacovigilance: Current Scenario and Emerging Trends

National Conference sponsored by GUJCOST on 03.08.2019 at SNLPCP, Umrakh

Download Brochure
News & Events
0.12
2018CiteScore
 
8th percentile
Powered by  Scopus
Google Scholar

hit counters free
0.07
2017CiteScore
 
11th percentile
Powered by  Scopus