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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Effect of TSH suppression therapy on serum minerals in newly diagnosed hypothyroid patients.

Author: VADIVEL.S
Abstract: Background: Thyroid disease is a pathological condition, which affects the calcium and phosphorous metabolism. Abnormalities in the calcium and phosphorous homeostasis are known as disorders of the mineral metabolism. Objective: To evaluate the effect of thyroid function on the serum calcium & phosphorus levels in newly diagnosed hypothyroid patients and to find out the effect of treatment on calcium and phosphorus levels. Methods & Materials: In this study the patients are aged between 20 – 60 yrs. 47 newly diagnosed hypothyroid patients were included in this study and find out the mineral alterations before and after the treatment in 47 patients. Estimation of the biochemical parameters was done by standard methods. Results: hypocalcaemia and hyperphosphatemia was observed before treatment in hypothyroid patients, but statistically not significant. Discussion & Conclusion: This study concluded that the S.Ca++ levels are decreased before treatment whereas S.PO4 - levels are increased. S.Ca++& S.PO4 not affected by gender. With the short duration of treatment serum Ca++& S.PO4 becomes normal.
Keyword: Calcium, Hypothyroidism, Phosphorus
DOI: https://doi.org/10.31838/ijpr/2019.11.03.093
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0.12
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