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Effect of TSH suppression therapy on serum minerals in newly diagnosed hypothyroid patients.
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| Author:
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VADIVEL.S
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| Abstract:
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Background: Thyroid disease is a pathological condition, which affects the calcium and phosphorous
metabolism. Abnormalities in the calcium and phosphorous homeostasis are known as disorders of the mineral
metabolism.
Objective: To evaluate the effect of thyroid function on the serum calcium & phosphorus levels in newly
diagnosed hypothyroid patients and to find out the effect of treatment on calcium and phosphorus levels.
Methods & Materials: In this study the patients are aged between 20 – 60 yrs. 47 newly diagnosed
hypothyroid patients were included in this study and find out the mineral alterations before and after the
treatment in 47 patients. Estimation of the biochemical parameters was done by standard methods.
Results: hypocalcaemia and hyperphosphatemia was observed before treatment in hypothyroid patients, but
statistically not significant.
Discussion & Conclusion: This study concluded that the S.Ca++ levels are decreased before treatment
whereas S.PO4 - levels are increased. S.Ca++& S.PO4 not affected by gender. With the short duration of
treatment serum Ca++& S.PO4 becomes normal.
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| Keyword:
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Calcium, Hypothyroidism, Phosphorus
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| EOI:
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| DOI:
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https://doi.org/10.31838/ijpr/2019.11.03.093
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| Download:
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Request For Article
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