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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

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Effect of Ambulation Time on the Neurological Complication after Spinal Anesthesia with Bupivacaine

Author: BANFSHEH MASHAK, FATEMEH BAYAT, SARA ESMAELZADEH SAEIEH, MITRA RAHIMZADEH, SEDIGHEH NOSRATI ABARGHOOEE, MINA ATAEI
Abstract: Introduction: Using spinal anesthesia has been increasingly used in cesarean and gynecological surgery. Bupivacaine is the golden standard for spinal anesthesia and cesarean surjery and it has been mainly used due to its ease of use and lower side effects. The current research aimed to compare the side effects after spinal anesthesia with bupivacaine in the early and late ambulation after spinal anesthesia with bupivacaine after cesarean surgery. Method: The present research is a randomized clinical trial, which was done on 230 candidate mothers for elective caesarean referring to the Kamali Hospital of Alborz Province in Iran. The sampling method was convenient and randomized via the random number tables and the participants were divided into the groups of the early ambulation less than 8 hours and late ambulation after 15 hours and the side effects of anesthesia with bupivacaine such as dizziness, difficulties deification, weakness, backache, headache, vomiting, urinary retention were compared by the means of Visual Analogue Scale (VAS) 8, 15, 24 and 72 hours after anesthesia and analyzed by SPSS software. Results: This research show that there is no difference in the side effects of anesthesia with Marcain ® (dizziness, difficulties deification, weakness, backache, headache, vomiting) in the ambulation 8 and 15 hours after delivery and there is just a difference in urinary retention 24 hours after surgery in the early and late ambulation groups and the urinary retention was just higher in one participant in the late ambulation group. Discussion: The results of the current research manifest that there is no difference in the side effects after early and late ambulation after spinal anesthesia with Bupivacaine and more researches are suggested to compare the side effects of other anesthesia drugs and in other times of ambulation
Keyword: Early ambulation, late ambulation, bupivacaine, neurologic complication, spinal anesthesia
DOI: https://doi.org/10.31838/ijpr/2019.11.04.116
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