IJPR  articles are Indexed in SCOPUSClick Here     Impact Factor for Five Years is 0.13 (2013 - 2018).    

logo

INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence

IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
ISSN
0975-2366
Current Issue
No Data found.
Article In Press
No Data found.
ADOBE READER

(Require Adobe Acrobat Reader to open, If you don't have Adobe Acrobat Reader)

Index Page 1
Click here to Download
IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

Click to download
 

Article Detail

Label
Label
SIMULTANEOUS DETERMINATION OF OFLOXACIN AND PREDNISOLONE ACETATE IN BINARY MIXTURE BY ABSORBANCE CORRECTION METHOD.

Author: PATEL DHARMENDRAKUMAR, SATISH A. PATEL, BANSARI D. PATEL
Abstract: A simple and sensitive spectrophotometric method based on absorbance correction was developed for the simultaneous estimation of Ofloxacin and Prednisolone Acetate in binary mixture. Absorbance correction method involves measurement of absorbance at 308 nm for estimation of Ofloxacin and measurement of corrected absorbance at 243 nm for estimation of Prednisolone acetate. The two drugs comply with beer’s-lambert’s law over the linearity range of 2-16 µg/ml for Ofloxacin and 5-35 µg/ml for Prednisolone acetate. The method was validated as per ICH guidelines in terms of linearity, accuracy (recovery study), precision (repeatability, intraday, interday precision), limit of detection and limit of quantification. All the validation parameters were found to be within acceptable limits. The method was found to be simple, sensitive, rapid, cost effective, accurate, and precise for the routine analysis of both the drugs in binary mixture.
Keyword: Ofloxacin, Prednisolone Acetate, Absorbance correction, Binary mixture, Validation.
Download: Request For Article
 












ONLINE SUBMISSION
USER LOGIN


Username
Password
Login | Register
News & Events
SCImago Journal & Country Rank

Terms and Conditions
Disclaimer
Refund Policy
Instrucations for Subscribers
Privacy Policy

Copyrights Form

0.12
2018CiteScore
 
8th percentile
Powered by  Scopus
Google Scholar

hit counters free