Impact Factor for Five Years is 1.55 (2012 - 2016). IJPRT Re-launched from 2017, for more details visit www.ijprtonline.com

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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

ISSN
0975-2366
5 - Years Impact Factor

Year 2012 - 2016

Impact Factor: 1.55

Total Publications: 317

Total Citation: 491

Year 2011 - 2015

Impact Factor: 1.46

Total Publications: 326

Total Citation: 477

Year 2010 - 2014

Impact Factor: 1.3

Total Publications: 313

Total Citation: 407

Year 2009 - 2013

Impact Factor: 0.973

Total Publications: 293

Total Citation: 285

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IJPRT ISSUE

January - March 6 [1] 2014

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Article Detail

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SIMULTANEOUS DETERMINATION OF OFLOXACIN AND PREDNISOLONE ACETATE IN BINARY MIXTURE BY ABSORBANCE CORRECTION METHOD.

Author: PATEL DHARMENDRAKUMAR, SATISH A. PATEL, BANSARI D. PATEL
Abstract: A simple and sensitive spectrophotometric method based on absorbance correction was developed for the simultaneous estimation of Ofloxacin and Prednisolone Acetate in binary mixture. Absorbance correction method involves measurement of absorbance at 308 nm for estimation of Ofloxacin and measurement of corrected absorbance at 243 nm for estimation of Prednisolone acetate. The two drugs comply with beer’s-lambert’s law over the linearity range of 2-16 µg/ml for Ofloxacin and 5-35 µg/ml for Prednisolone acetate. The method was validated as per ICH guidelines in terms of linearity, accuracy (recovery study), precision (repeatability, intraday, interday precision), limit of detection and limit of quantification. All the validation parameters were found to be within acceptable limits. The method was found to be simple, sensitive, rapid, cost effective, accurate, and precise for the routine analysis of both the drugs in binary mixture.
Keyword: Ofloxacin, Prednisolone Acetate, Absorbance correction, Binary mixture, Validation.
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News & Events
Impact Factor for five years is 1.55 (2012 - 2016)
Year 2011 - 2015 Impact Factor - 1.46 Total Publications - 326 Total Citations - 477
Impact Factor for five years is 1.3 (2010 - 2014)