IJPR  articles are Indexed in SCOPUSClick Here     Impact Factor for Five Years is 0.13 (2013 - 2018).    

logo

INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence

IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
ISSN
0975-2366
Current Issue
No Data found.
Article In Press
No Data found.
ADOBE READER

(Require Adobe Acrobat Reader to open, If you don't have Adobe Acrobat Reader)

Index Page 1
Click here to Download
IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

Click to download
 

Article Detail

Label
Label
DEVELOPMENT AND VALIDATION OF SPECTROPHOTOMETRIC METHOD FOR SIMULTANEOUS ESTIMATION OF MOXIFLOXACIN AND PREDNISOLONE ACETATE IN EYE DROP

Author: PATEL BHAILALBHAI, SATISH A. PATEL, PINAL B. PATEL
Abstract: A simple and sensitive spectrophotometric method based on absorbance correction was developed for the simultaneous estimation of Moxifloxacin and Prednisolone Acetate in pharmaceutical dosage form. Absorbance correction method involves measurement of absorbance at 330 nm for estimation of Moxifloxacin and measurement of corrected absorbance at 243 nm for estimation of Prednisolone acetate. The two drugs comply with beer’s-lamberts’ law over the linearity range of 5 to 40 µg/ml for Moxifloxacin and 4 to 32 µg/ml for Prednisolone acetate. The method was validated as per ICH guidelines in terms of linearity, accuracy (recovery study), precision (repeatability, intraday, interday precision), limit of detection and limit of quantification. All the validation parameters were found to be within acceptable limits. The method was found to be simple, sensitive, rapid, cost effective, accurate, and precise for the routine analysis of both the drugs in pharmaceutical dosage form.
Keyword: Moxifloxacin, Prednisolone Acetate, Absorbance correction method, spectrophotometric, pharmaceutical dosage form, validation
Download: Request For Article
 












ONLINE SUBMISSION
USER LOGIN


Username
Password
Login | Register
News & Events
SCImago Journal & Country Rank

Terms and Conditions
Disclaimer
Refund Policy
Instrucations for Subscribers
Privacy Policy

Copyrights Form

0.12
2018CiteScore
 
8th percentile
Powered by  Scopus
Google Scholar

hit counters free