Impact Factor for Five Years is 1.55 (2012 - 2016). IJPRT Re-launched from 2017, for more details visit www.ijprtonline.com

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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
ISSN
0975-2366
5 - Years Impact Factor

Year 2012 - 2016

Impact Factor: 1.55

Total Publications: 317

Total Citation: 491

Year 2011 - 2015

Impact Factor: 1.46

Total Publications: 326

Total Citation: 477

Year 2010 - 2014

Impact Factor: 1.3

Total Publications: 313

Total Citation: 407

Year 2009 - 2013

Impact Factor: 0.973

Total Publications: 293

Total Citation: 285

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January - March 6 [1] 2014

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Article Detail

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DEVELOPMENT AND VALIDATION OF SPECTROPHOTOMETRIC METHOD FOR SIMULTANEOUS ESTIMATION OF MOXIFLOXACIN AND PREDNISOLONE ACETATE IN EYE DROP

Author: PATEL BHAILALBHAI, SATISH A. PATEL, PINAL B. PATEL
Abstract: A simple and sensitive spectrophotometric method based on absorbance correction was developed for the simultaneous estimation of Moxifloxacin and Prednisolone Acetate in pharmaceutical dosage form. Absorbance correction method involves measurement of absorbance at 330 nm for estimation of Moxifloxacin and measurement of corrected absorbance at 243 nm for estimation of Prednisolone acetate. The two drugs comply with beer’s-lamberts’ law over the linearity range of 5 to 40 µg/ml for Moxifloxacin and 4 to 32 µg/ml for Prednisolone acetate. The method was validated as per ICH guidelines in terms of linearity, accuracy (recovery study), precision (repeatability, intraday, interday precision), limit of detection and limit of quantification. All the validation parameters were found to be within acceptable limits. The method was found to be simple, sensitive, rapid, cost effective, accurate, and precise for the routine analysis of both the drugs in pharmaceutical dosage form.
Keyword: Moxifloxacin, Prednisolone Acetate, Absorbance correction method, spectrophotometric, pharmaceutical dosage form, validation
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News & Events
Impact Factor for five years is 1.55 (2012 - 2016)
Year 2011 - 2015 Impact Factor - 1.46 Total Publications - 326 Total Citations - 477
Impact Factor for five years is 1.3 (2010 - 2014)