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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Screening Of Some Fruits for Its Antipyretic Potential.

Author: UPLOADED BY-ADMIN, BIREN N. SHAH, A.K. SETH
Abstract: The objective of the present work was to study the antipyretic activity of fruits of Lagenaria siceraria, Trichosanthes dioica and Abelmoschus esculentus. The Methanolic and aqueous extracts of fruits of all plants were taken for the study and evaluated for antipyretic activity using Brewer’s yeast induced pyrexia in wistar strain albino rats. Methanolic extract (39.35 ± 0.08) and aqueous extract (39.58 ± 0.51) of Lagenaria siceraria does not show any significant antipyretic activity. At 90 min interval methanolic extract (37.82 ± 0.36) of Trichosanthes dioica shows moderately significant activity, while after 180 min the methanolic extract (36.57 ± 0.31) shows highly significant activity. The aqueous extract (38.10 ± 0.11) of Trichosanthes dioica fruit were failed to show any significant antipyretic activity. At 90 min interval methanolic extract (37.98 ± 0.22) of Abelmoschus esculentus shows moderately significant activity, while after 180 min the methanolic extract (36.12 ± 0.23) shows highly significant activity, when compared with the control (39.62 ± 0.09) and standard (36.18 ± 0.28). The aqueous extract (38.23 ± 0.09) of Abelmoschus esculentus fruits were failed to show any significant antipyretic activity.
Keyword: Lagenaria siceraria, Trichosanthes dioica, Abelmoschus esculentus, Antipyretic activity, Brewer’s yeast.
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