IJPR  artciles are Indexed in SCOPUSClick Here     Impact Factor for Five Years is 1.55 (2012 - 2016). 

logo

INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence

IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

ISSN
0975-2366
5 - Years Impact Factor

Year 2012 - 2016

Impact Factor: 1.55

Total Publications: 317

Total Citation: 491

Year 2011 - 2015

Impact Factor: 1.46

Total Publications: 326

Total Citation: 477

Year 2010 - 2014

Impact Factor: 1.3

Total Publications: 313

Total Citation: 407

Year 2009 - 2013

Impact Factor: 0.973

Total Publications: 293

Total Citation: 285

Current Issue
22nd NATIONAL CONVENTION

22nd National Convention of Society of Pharmacognosy & International Conference. For more details visit


For More Detail Visit ncsp.ganpatuniversity.ac.in
Article In Press
ADOBE READER

(Require Adobe Acrobat Reader to open, If you don't have Adobe Acrobat Reader)

Index Page 1
Click here to Download
IJPRT ISSUE

January - March 6 [1] 2014

Click to download
IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

Click to download
PIPPHARMACON & IJPR 2018

PIPPHARMACON & IJPR 2018

Click to download
 

Article Detail

Label
Label
Analytical Method Development and Validation for the Simultaneous Estimation of Ambroxol Hydrochloride and Guaiphenesin in Syrup Dosage form by RP-HPLC

Author: AZHAR KHAN, VANDANA JAIN, OJASWI GHADGE, SUDHA RATHOD
Abstract: A simple, rapid, accurate and precise reverse phase-high performance liquid chromatographic (RP-HPLC) method has been developed and validated for the simultaneous determination of Ambroxol hydrochloride and Guaiphenesin in combined dosage form. Separation was performed using Phenomex C18 column (250*4.5 mm, 0.5 µ) on LC-20 AD Prominence Liquid chromatograph (Shimadzu, Japan) attached with Spd-20A/20AV Prominence SPD-20A prominence UV/Vis detector, by using mobile phase0.02 M Potassium dihydrogen orthophosphate (pH 3.5) and Acetonitrile (30:70 V/V) isocratic elution using a flow rate of 1mL/min. Good sensitivity was observed with UV detection at 215 nm. Retention times of Ambroxol hydrochloride and Guaiphenesin were found to be about 2.39 and 2.90 min, respectively. The method was validated over the range from 3-18µg/mL for Ambroxol hydrochloride and 20-120 µg/mL for Guaiphenesin with correlation coefficients of 0.996 and 0.997, respectively. This method was shown to be accurate, specific, robust, linear, and repeatable and can be successfully employed in routine quality control for the simultaneous analysis of Ambroxol hydrochlorideand Guaiphenesin in syrup.
Keyword: Ambroxol hydrochloride, Guaiphenesin, RP-HPLC, Syrup dosage form.
Download: Request For Article
 












USER LOGIN


Username
Password
Login | Register
AICTE INTERNATIONAL CONFERENCE

AICTE Sponsored International Conference on Challenges, Opportunities and Newer Directions of Pharmacovigilance and Clinical Research in India

Download Brochure


For More Detail Visit www.pippharmacon.org
News & Events

CiteScore 2016 -  0.09

SJR 2016 - 0.111

SNIP 2016 - 0.055

Impact Factor for five years is 1.55 (2012 - 2016)
Year 2011 - 2015 Impact Factor - 1.46 Total Publications - 326 Total Citations - 477
Impact Factor for five years is 1.3 (2010 - 2014)