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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
ISSN
0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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IN-VITRO ANTI-INFLAMMATORY ACTIVITY OF LIQUORICE AND CATECHU BY HRBC MEMBRANE STABILIZING ACTIVITY

Author: KESHA DESAI, RAMESH K. GOYAL, DINESH R.SHAH
Abstract: India is one of the countries where different traditional systems of medicines are practiced. These systems depend upon plant resources to great extent for the raw materials. Herbal medicine is still the mainstay of about 75–80% of the world’s population, mainly in developing countries, for primary health care because of better cultural acceptability, better compatibility with the human body and lesser side effects. Aphthous stomatitis (Canker sores) are small oval sores, red in colour, that affect the mucous membranes inside the mouth that are usually developed on the inner cheeks, gums or lips and occasionally the tongue. There is intense or moderate pain and it heals in about 10 - 14 days for the more common type and more than 2 weeks for the severe type. In in- vitro study on LC demonstrated the depression of inflammation. Stabilization of the HRBCs membrane by Carrageenan-induced inflammation was studied to establish the mechanism of anti-inflammatory action of LC. Therefore, our present in vitro study on LC demonstrates the depression of inflammation. Due to the presence of active principle such as tannin may responsible for this activity.Hence, LC can be used as a potent anti inflammatory agent.
Keyword: RAS (Recurrent Aphthous Stomatitis), LC (Liquorice and Catechu), HRBC (Human Red Blood Cells)
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0.12
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