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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Study of acute and subchronic toxicity of "phytodiabetol"

Author: ALLAEVA ,, DILSHOD ACHILOV, MAKHSUMOV SHARAFIDDIN, MAMADJANOVA MUNIRAKHON
Abstract: At long intestinal influence of vegetative gathering of food "Phytodiabetol" changes from the side of hematological and biochemical parameters, in particular indicators of alkaline phosphatase, transaminase enzymes (ALT, AST) in blood serum are not revealed. Absence of obvious deviations from the norm of such biochemical parameters indicates low toxicity of this drug. The studied preparation in doses of 6 and 60 mg/kg has no negative effect on blood glucose level. There is a decrease in the concentration of glucose in the blood from the upper limit of the norm to the lower limit of the norm and it may be associated with its sugar-reducing activity. The results of histomorphological studies of tissues of internal organs in the long intestinal tract of administration of dietary supplements to food "Fitodiabetol" confirm the absence of toxic effects on internal organs.
Keyword: Phytodiabetol
DOI: https://doi.org/10.31838/ijpr/2019.11.04.064
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