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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Optimization of composition and development of technology for capsules of dry extract of Cichorium Intybus l.

Author: JALILOV MAMARAHIMOVICH, KAMBAROV KHUSAN DJAHANGIROVICH, FAYZULLAEVA NODIRA SULTANOVNA, BEKCHANOV KHAMDAM KUZIEVICH, KARIEVA EKUT SAIDKARIMOVNA
Abstract: To find the optimal combination of active and auxiliary substances, as well as to optimize the technology of capsules of dry extract of chicory, the method of mathematical planning of the experiment was used in order to minimize the consumption of materials and waste of time. At the same time, fillers, glidants, disintegrants and binders were studied as factors affecting optimization criteria, and flowability, bulk density, angle of repose of capsule mass and capsule disintegration were studied as optimization criteria.
Keyword: Cichorium intybus L., dry extract, method, mathematical planning of the experiment, factor, optimization criteria, capsules of dry extract of Cichorium intybus, excipients.
DOI: https://doi.org/10.31838/ijpr/2019.11.04.060
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