Antioxidant and Anti-Radical Effects ofQuercetin and Rutin: Methyl Linoleate Model
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Author:
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L.A. ZHURAVLEVA, S.S. ZYKOVA, V.S. TALISMANOV, ?.G. KARMANOVA
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Abstract:
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Volumetrically, by the method of external standard (ionol), a comparative evaluation of the antioxidant (AO) and antiradical
activity (ARA) of individual flavonoids of quercetin and rutin was conducted under conditions of homogeneous
kinetic model of oxidation of methyl linoleate.The manifestation of a higher AOA quercetin in the range of studied
concentrations of 9.8·10?6 - 1·10?2mol/l was established. A number of reducing the AOA compounds:
quercetin>rutin>ionol was received. It was established that at a concentration of 2·10-5mol/l and smaller ARA
quercetin is 4.8 and 1.6 times higher than ARA rutin and ionol, respectively. A simple mechanism of action of
quercetin and rutin at concentrations of less than 2.0·10?5mol/l, i.e. participation only in chain breakage reactions; for
concentrations of greater 2.0·10?5mol/l, the participation of the inhibitors under study in chain continuation reactions
and a higher ARA of quercetin than rutin was established.
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Keyword:
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antiradical activity, antioxidant activity, free radical oxidation, homogeneous oxidation, quercetin, rutin
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EOI:
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DOI:
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https://doi.org/10.31838/ijpr/2019.11.04.027
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