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Study of Aminoacy lt RAN-SynthetaseComplex Interacting Multifunctional Protein 1 and Liver Enzymes in Iraqi Women with Breast Cancer Undergoing Chemotherapy
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| Author:
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EIMAN A., BAYADER ABDUL HUSSEIN
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| Abstract:
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Breast carcinoma is one of the greatest popular neoplasms in females. It is a major reason of demise in the world, and
it is the first cancer in ranking diagnosed in Iraqi women. This study aimed to determine aminoacyltRAN-synthetase
complex interacting multifunctional protein 1 and liver enzymes levels in Iraqi females with stage II breast malignance,
and study the effect of chemotherapy (after surgery) on these markers. This study included 50 females patients with
stage II breast malignance (before and after surgery and second dose of chemotherapy) attending the Oncology
Teaching Hospital in Medical City/ Baghdad, in addition to 20 persons as controller group were chosen without any
chronic diseases. Their ages ranged from (30-55) years. The results shown elevation inaminoacyltRAN-synthetase
complex interacting multifunctional protein 1, CA15-3, liver function test levels, while there was a decrease in
magnesium level in serum of females with stage II breast malignance before and after two dose chemotherapy when
compared with the controls. The current revision is the first in follow-up of aminoacyltRAN-synthetasecomplex
interacting multifunctional protein 1 level in serum of women patients with breast malignance before and after
chemotherapy treatment. The aminoacyltRAN-synthetase complex interacting multifunctional protein 1may be a new
bio-marker in breast malignance. Because the elevation in liver enzymes and decrease in magnesium levels, these
patients may be more prone to liver damage, and the magnesium may be as a chemo-preventive agent from breast
cancer because the inverse relationship between the magnesium and this disease.
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| Keyword:
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Breast cancer, Chemotherapy, AminoacyltRAN-synthetase complex interacting multifunctional protein 1.
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2019.11.04.002
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| Download:
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