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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Upper respiratory tract infections children caused by viruses (URTI)

Author: DR.ABEER ABDULQADER, MR(S).BUSHRA ISMAIL IBRAHIM
Abstract: The study was aimed at determining bacterial agents of the upper respiratory tract and the susceptibility patterns of isolates to antibiotics. In total, 250patients who attending Salah Aldin Hospital,gynecology and pediatric teaching hospital and Samarra Hospital who complain of respiratory complication have been Screened to obtain the prevalence of respiratory pathogens and to understand the antibiotic susceptibility patterns of isolates using standard microbiological procedure and the disc-diffusion test. Of the 250 samples screened, 182 (72.8%) had upper RTIs according to physical diagnosis of physicians that include (64.8%) had viral infection and (35.1) had bacterial infection .cultures with the dominant bacterial pathogens being Haemophilusinfluenzae (40.6%), followed by Streptococcus pneumoniae (28%), Klebsiellapneumoniae (17.1%), and Staphylococcus aureus (9%). Although 67% of the isolates were recovered from females compared to 32.9% from males, the difference was not statistically significant (p>0.05). the pathogens were isolated from the age-group of 10-13 years was 22.5%, while 34.6% from the age-group of 1-3 years, and 12% from the age-group of 10-12 years. Antibiotic susceptibility testing revealed that gentamicin (92%) and cefuroxime (88.4%) were the most effective antibiotics against the isolates. Generally, susceptibility ranged from 0% to 92% depending on the antibiotic and the species of microorganism. Penicillin had the highest (100%) resistance to all the isolates. Although multidrug-resistant strains of organisms were identified, gentamicin and cefuroxime are recommended as the first-line antibiotics of choice against the pathogens.
Keyword: Haemophilusinfluenzae, URTI
DOI: https://doi.org/10.31838/ijpr/2019.11.03.106
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