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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Systematic Evaluation of Drug Prescribing Patterns and Utilization in Coronary Artery Disease Patients at Tertiary Care Hospital in Delhi

Author: KAVITA BANSAL, SATYENDRA KUMAR RAJPUT, VINOD SHARMA, V. S. MATHUR
Abstract: The coronary artery disease (CAD) is proven to be one of the biggest reasons for CVD, especially in India. The objective of this study is to analyze patterns of drug-utilization among CAD patients admitted in Tertiary care hospital. A total of 236 patients were considered having mean age 60.45±10.78 years. Of all, 75.85% were males and 89.83% were above 45 years of age. The average hospital stay was 4.32 days (95% CI: 4.04-4.61). No significant difference was observed in hospitalization duration among male (4.23 days, 95% CI: 3.91-4.55) as compared to female (4.45 days, 95% CI: 4.13-4.87, p>0.10). The most common categories of drugs prescribed were Antiplatelets (95.34%), Statins (88.56%), Anti-anginal (82.20%), Beta-blockers (69.07%), and ACE-inhibitors (45.76%). Average drugs prescribed per patient was 12.47 (95% CI: 12.14-12.81). However, the average cardiovascular drugs prescribed was 5.83 only (95% CI: 5.48-6.14). Almost 82.20% patients were identified with Poly-pharmacy (>5 drugs). Antiplatelets and Statins were identified as most popular drug categories. Clopidogrel (B01AC04) and Atorvastatin (C10AA05) were most commonly prescribed drugs for Antiplatelets and Statins. The most common co-morbidities associated with CAD patients were Hypertension (48.73%) and Diabetes Mellitus (36.02%).
Keyword: Drug utilization, coronary artery disease, poly-pharmacy
DOI: https://doi.org/10.31838/ijpr/2019.11.03.019
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