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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

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0975-2366
5 - Years Impact Factor

Year 2012 - 2016

Impact Factor: 1.55

Total Publications: 317

Total Citation: 491

Year 2011 - 2015

Impact Factor: 1.46

Total Publications: 326

Total Citation: 477

Year 2010 - 2014

Impact Factor: 1.3

Total Publications: 313

Total Citation: 407

Year 2009 - 2013

Impact Factor: 0.973

Total Publications: 293

Total Citation: 285

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Total Phenol Content and Antioxidant activity of Various Concentration of Ethanol Extract of Psidium Guajava L

Author: MUSTOFA AHDA, WAHYU TIKA LESTARI, RIRIN LESTARI SRI RAHAYU
Abstract: Objective: This research has studied the total phenolic content and antioxidant activity from extract ethanol of Psidium Guajava L and also determine both the total phenolic content and antioxidant activity correlation. Methods: The extraction processes of guava leaf use ethanol solvents with the different concentration that are ethanol 96%, 80%, 50% 20% and also water. The guava leaf extract was obtained will be identified the phytochemical component and determined the total phenol content using Folin Ciocalteu method and also verified their antioxidant activity to DPPH. Results: Generally, the extracts of Psidium Guajava L. contain some active compounds as phenol content, saponin, flavonoid, and alkaloid. However, the effect of solvent in the extraction lead the active compound from Psidium Guajava L is different. The water extract of Psidium Guajava L does not contain any active compound like ethanol extract of Psidium Guajava L. Whereas, the water extract of Psidium Guajava L has less amount total phenolic content and less potency of antioxidant activity than the ethanol extract of Psidium Guajava, possessing as good antioxidant. Conclusion: This research has indicated that the different solvents can lead and result in the different species of the active compounds. The 80% ethanol extract of Psidium Guajava L has the highest antioxidant activity with the IC50 value of 7.73±0.7 µg/mL.
Keyword: Total Phenol Content, Antioxidant Activity, Psidium Guajava L
DOI: https://doi.org/10.31838/ijpr/2019.11.03.078
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Impact Factor for five years is 1.55 (2012 - 2016)

Year 2011 - 2015 Impact Factor - 1.46 Total Publications - 326 Total Citations - 477