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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
ISSN
0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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A narrative review of thallium toxicity; preventive measures

Author: RAZIE EGHTESADI, SOMAYE SAFAVI, FATEMEH SHAHMIRZAYI, HAMID REZA BANAFSHE, SEPEHR OMIDI, AMIR GHADERI
Abstract: Thallium (Tl) toxicity is an important clinical disease and its effects on the human body are devastating. Tl poisoning is an important health issue in many countries in the world. Thallium is a toxic heavy metal that exists in nature. Tl toxicity may occur in food and drinking water, occupational exposure, environment (air, industrial combustion of coal, water, and plants), arable soils and vegetables, aquatic and terrestrial animals, prenatal thallium exposure, illicit drugs, cigarette smokers. Adding lead to the opium is a recently health hazard that has been observed among opioid poisoned patients. The clinical manifestation of Tl poisoning has a wide spectrum but painful ascending peripheral neuropathy, gastrointestinal, and dermatologic manifestations are major characteristics in Tl toxicity. The toxicity of thallium based compounds is mainly caused by the similarity between TL ions and potassium ions, which results in the disorder of potassium associated metabolic processes due to thallium interference. The aim of this review is to assess identify eliminate, sources or control sources, and environmental exposures and hazards to prevent thallium toxicity.
Keyword: Thallium, Poisoning, Toxicity
DOI: https://doi.org/10.31838/ijpr/2019.11.03.053
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0.12
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