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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Molecular study of Polymorphisms In Uromodulin supporter Region In Patients With Hypertension In Babylon prefecture

Author: SDDIQGHANI AL-MUHANNA, ISRAA ABDUL AMEER AL-KRAETY, ZAINAB MOHAMMED JASSIM
Abstract: Hypertension disease characterize an intense health issue for improving countries. grant to the studies of the world health organization (WHO), that about 40% of adults Iraqi suffered from hypertension. Some causes of infrequent monogenic lead to hypertension, but the predominance of hypertension is likely to be multifactorial disorder, due to interference of environmental and genetic factors. Outcome of PCR-SSCP for uromodulin promoter gene illustrated that two several haplotypes confer to the numbers of the bands in the uromodulin promoter gene containing bands 4 and 5 . But, these haplotype was reveal among two groups; in hypertension patient groups and control, results appear that was related among bands4 and 5 in patients as contrast with group control .
Keyword: hypertension , uom ,promoter ,SSCP, PCR, GFR ,SNP
DOI: https://doi.org/10.31838/ijpr/2019.11.03.038
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