URATE REGULATION GENE POLYMORPHISMS ARE CORRELATED WITH CLINICAL FORMS OF CORONARY HEART DISEASE
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Author:
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, TASHKENBAEVA ELEONORA NEGMATOVNA, ZIYADULLAEV SHUKHRAT KHUDAYBERDIEVICH, KAMALOV ZAYNITDIN SAYFUTDINOVICH, TOGAEV DILSHOD KHIDIRNAZAROVICH, KADIROVA FARZONA SHUKHRATOVNA, ABDIEVA GULNORA ABDULLAEVNA
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Abstract:
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Coronary heart disease is one of the most common cardiovascular diseases and a main cause of death and disability in
the modern world. The roles of various external and internal factors in the etiology and pathogenesis of coronary
heart disease must be established. The purpose of this study was to study the relationship of single nucleotide
polymorphisms of the genes GLUT9 and URAT1 with coronary heart disease in the Uzbek population. The results of
our study showed the importance of the polymorphic variants of URAT1 and GLUT9 in the genetic predisposition to
coronary heart disease among the Uzbek population.
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Keyword:
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Heart Disease, Polymorphism, Single Nucleotide, Genetic Association Studies
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EOI:
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-
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DOI:
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https://doi.org/10.31838/ijpr/2019.11.03.032
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