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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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THE STUDY OF THE POLYMORPHIC GENE AGTR1 1166 A> C AND A MARKER OF NEPHRINE WITH DIABETIC NEPHROPATHY IN PATIENTS WITH TYPE 1 DIABETES IN THE UZBEK POPULATION

Author: , RAKHIMBERDIYEVA ZIYODA AKZAMOVNA, SHAGAZATOVA BARNO XABIBULLAYEVNA, NAJMUTDINOVA DILOROM KAMARDINOVNA, BOBOYEV QODIR TOXTABAYEVICH
Abstract: In this study, the distribution of the frequencies of AGTR1 alleles and genotypes was first studied, and an association of polymorphic markers 1166 A> C in the AGTR1 gene was detected in patients with type 1 diabetes in the Uzbek population, and an early marker of nephrin in serum was detected in 32.5% of patients development of increased albumin excretion, which indicates the possibility of using this protein as an early prognostic marker of diabetic nephropathy in patients with type 1 diabetes.
Keyword: type 1 diabetes, diabetic nephropathy, gene AGTR1 1166 A> C, nephrine.
DOI: https://doi.org/10.31838/ijpr/2019.11.03.030
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0.12
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