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THE STUDY OF THE POLYMORPHIC GENE AGTR1 1166 A> C AND A MARKER OF NEPHRINE WITH DIABETIC NEPHROPATHY IN PATIENTS WITH TYPE 1 DIABETES IN THE UZBEK POPULATION
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| Author:
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, RAKHIMBERDIYEVA ZIYODA AKZAMOVNA, SHAGAZATOVA BARNO XABIBULLAYEVNA, NAJMUTDINOVA DILOROM KAMARDINOVNA, BOBOYEV QODIR TOXTABAYEVICH
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| Abstract:
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In this study, the distribution of the frequencies of AGTR1 alleles and genotypes was first studied, and an association
of polymorphic markers 1166 A> C in the AGTR1 gene was detected in patients with type 1 diabetes in the Uzbek
population, and an early marker of nephrin in serum was detected in 32.5% of patients development of increased
albumin excretion, which indicates the possibility of using this protein as an early prognostic marker of diabetic
nephropathy in patients with type 1 diabetes.
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| Keyword:
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type 1 diabetes, diabetic nephropathy, gene AGTR1 1166 A> C, nephrine.
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2019.11.03.030
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| Download:
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