IJPR  articles are Indexed in SCOPUSClick Here     Impact Factor for Five Years is 0.13 (2013 - 2018).    

logo

INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence

IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
ISSN
0975-2366
Current Issue
Article In Press
Prevalence and Risk Factors of Occupation Induced Asthma among Traffic Police in Bangalore City
o Estimate the Prevalence of Depression, Anxiety, and Stress among Adolescents in Kancheepuram District, Tamil Nadu
A Study on Risk Factors of Anaemia among Pregnant Women
n Approach of Nutritional Deficiency Disorder among Pregnant Women
The Determinants of Self Care Practices By Using DSME to Facilitate the Patients In Kanchipuram District
An evaluation of Epidemiological Factors Relating to Overweight, Obesity in Urban Chennai
A study on the Pattern of Body Image Perception among Adolescents in Urban Chennai
mpact of an External and Internal factors of overweight and obesity in urban
A study on Anti-Rabies Vaccine among Dog Bite Victims in chennai region
Hospital Based Cross Sectional Study: Distribution of Compliance for completion of ARV 4 dose among study participants
12345678910...
ADOBE READER

(Require Adobe Acrobat Reader to open, If you don't have Adobe Acrobat Reader)

Index Page 1
Click here to Download
IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

Click to download
 

Article Detail

Label
Label
Drug Utilization Evaluation of Higher End Antibiotics inan Intensive Medical Care Unit ofa Tertiary Care Hospital

Author: JENI SHARON, BONISH ROMANCE, LAKSHMI S, JASNOSAJI JOHN, BABUN, AARTHIPRAKASAM, S.RAMALAKSHMI
Abstract: Intensive care unit (ICU) requires emergent coverage with empirical broad-spectrum antibiotics, with a subsequentde-escalation based on culture report. Antimicrobial resistance has emerged as an important determinant of outcome for patients in the intensive care unit. Hence, the present study was aimed to evaluate the prescriptions with higher end antibiotics among critically ill patients. This was aprospective cross sectional observational study conducted in the Intensive Medical Care Unit of a tertiary care hospital in Chennai for a period of 6months. The data of patients prescribed with the selected higher end was collected using a pre-structured data entry form. Theantibiotics prescribed were analysed for appropriateness based on several criteria with the Hospital antibiotic policy.A total of 271 high end antibiotics were prescribed for 160 patients of which PiperacillinTazobactam (33.5%) and Meropenem (30.6%) were predominant. About 70.11% were on empiric therapy and 29.8% were on definitive therapy based on culture test. The most prevailing organism was found to beEscherichiacoli(35.8%). There was an increase in resistance to PiperacillinTazobactamtowardsEscherichiacoli (39.4%), Klebsiella pneumonia (55%) and Acinetobacterbaumannii(71.4%). Prescription analyses indicate, 18.45 % of inappropriateness. The main reason for inappropriateness was with respect to dosage adjustment (11 %), dosing interval (9.22 %) anddose (7.38%).There was a satisfactory standard has maintained inthe hospital. However, dosing adjustment in renalpatient need further intervention to improve the quality of health care
Keyword: Drug Utilisation Evaluation, Antimicrobial Resistance, Restricted Antibiotic
DOI: https://doi.org/10.31838/ijpr/2019.11.03.022
Download: Request For Article
 












ONLINE SUBMISSION
USER LOGIN


Username
Password
Login | Register
News & Events
0.12
2018CiteScore
 
8th percentile
Powered by  Scopus
Google Scholar

hit counters free
0.07
2017CiteScore
 
11th percentile
Powered by  Scopus