Trophoblastic Choriocarcinoma with Metastasis to Kidney and Lung : Case Report
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Author:
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ZOHREH CHITSAZI, TAHEREH MOSHKELGOSHA ARDEKANI, MEHRNAZ KHERAD, SEYED SAADAT GHOLAMI
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Abstract:
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Background: Choriocarcinoma is a highly malignant form of gestational trophoblastic disease. It is characterized by
metastatic potential, rapid growth and deeply invasion into blood vessel and then widespread dissemination
metastasis. However, the most common sites of metastatic choriocarcinoma are lung, vagina, liver,kidney and brain.
But, metastatic choriocarcinomas rarely is extended to pulmonary and urinary system. It is important to keep in mind
that despite extensive metastasis, choriocarcinoma is very curable disease. Due to high responsibility of this disease,
early diagnosis of choriocarcinoma and treatment with chemotherapy can prevent mortality and morbidity of these
patients. In this case report, we present a rare case of metastatic choriocarcinoma in the kidney and lung after
normal term pregnancy.
Case presentation: The patient is a female who has 33 years old. G3Ab2(G1 she had curettage in second month of
pregnancy 4 years ago and G2 Second month aborted involuntary 5 month ago.
Conclusion :In abnormal postpartum hemorrhage, we should consider the possibility of choriocarcinoma. Although, it
is important to note rare manifestations of metastatic choriocarcinoma of kidney and lung with bleeding .
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Keyword:
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choriocarcinoma, kidney, lung, metastasis, trophoblastic disease, un normal uterus bleeding
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DOI:
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