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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Trophoblastic Choriocarcinoma with Metastasis to Kidney and Lung : Case Report

Author: ZOHREH CHITSAZI, TAHEREH MOSHKELGOSHA ARDEKANI, MEHRNAZ KHERAD, SEYED SAADAT GHOLAMI
Abstract: Background: Choriocarcinoma is a highly malignant form of gestational trophoblastic disease. It is characterized by metastatic potential, rapid growth and deeply invasion into blood vessel and then widespread dissemination metastasis. However, the most common sites of metastatic choriocarcinoma are lung, vagina, liver,kidney and brain. But, metastatic choriocarcinomas rarely is extended to pulmonary and urinary system. It is important to keep in mind that despite extensive metastasis, choriocarcinoma is very curable disease. Due to high responsibility of this disease, early diagnosis of choriocarcinoma and treatment with chemotherapy can prevent mortality and morbidity of these patients. In this case report, we present a rare case of metastatic choriocarcinoma in the kidney and lung after normal term pregnancy. Case presentation: The patient is a female who has 33 years old. G3Ab2(G1 she had curettage in second month of pregnancy 4 years ago and G2 Second month aborted involuntary 5 month ago. Conclusion :In abnormal postpartum hemorrhage, we should consider the possibility of choriocarcinoma. Although, it is important to note rare manifestations of metastatic choriocarcinoma of kidney and lung with bleeding .
Keyword: choriocarcinoma, kidney, lung, metastasis, trophoblastic disease, un normal uterus bleeding
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