IJPR  articles are Indexed in SCOPUSClick Here     Impact Factor for Five Years is 0.13 (2013 - 2018).    

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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

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0975-2366
5 - Years Impact Factor

Year 2012 - 2016

Impact Factor: 1.55

Total Publications: 317

Total Citation: 491

Year 2011 - 2015

Impact Factor: 1.46

Total Publications: 326

Total Citation: 477

Year 2010 - 2014

Impact Factor: 1.3

Total Publications: 313

Total Citation: 407

Year 2009 - 2013

Impact Factor: 0.973

Total Publications: 293

Total Citation: 285

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N-acetylcysteine in addiction management: current knowledge and future perspectives

Author: AMIR GHADERI, NEDA VAHED, RAOOFEH GHAYOOMI, VAHIDREZA OSTADMOHAMMADI, MOSTAFA GHOLAMI, SOMAYEH GHADAMI DEHKOHNEH
Abstract: Drug abuse disorders and addictive behaviors are serious public health problems and major contributors to the global burden of disease. Previous studies show that N-acetylcysteine (NAC) may be involved in neurodevelopment adult brain. The potential neuroprotective effect of NACis associated with modulate several neurological pathways, including prevention of oxidative stress or inflammation damage to nervous tissue and glutamate dysregulation, NAC is being explored as an adjunctive therapy for drug addiction and addiction management.We here review the role of NAC in the addiction, such as cannabis abuse, methamphetamine abuse, cocaine addiction, nicotine dependency, and gambling.Adequate administrate of NAC seems to be crucial in terms of addiction management. NAC is safe and well tolerated when administered orally but has documented risks with intravenous administration. An evidence study supports its use as an adjunctive therapy clinically for drug addiction, administered concomitantly with existing medications. The aim of this review is to assess the current knowledge related to the role of NAC administration on drug addiction and addiction management.
Keyword: N-acetylcysteine (NAC), drug addiction, addiction management
DOI: https://doi.org/10.31838/ijpr/2019.11.03.003
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0.12
2018CiteScore
 
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0.07
2017CiteScore
 
11th percentile
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Impact Factor for five years is 1.55 (2012 - 2016)

Year 2011 - 2015 Impact Factor - 1.46 Total Publications - 326 Total Citations - 477