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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Microwave assisted eco friendly synthesis of pharmaceutically important azomethine analogues employing bio degradable polyacrylic acid as catalyst and water as solvent

Author: POOJA BEDI, TANAY PRAMANIK
Abstract: The present paper describes an ecofriendly and economical method for the synthesis of azomethines by using ptoluidine and various aromatic aldehydes as reactants. All the reactions were performed under microwave irradiation and the reactions were catalyzed by aqueous solution of polyacrylic acid which is a biodegradable polymer. A proper choice of the solvent and reaction conditions allowed the final products to be generated in excellent yields in a onestep procedure. Microwave irradiation method gives advantages like reduction in reaction time and increase in percentage yield. The structures of synthesized compounds were confirmed by melting point, IR, H1-NMR, C13-NMR spectroscopy.
Keyword: microwave, green synthesis, azomethine, polyacrylic acid
DOI: https://doi.org/10.31838/ijpr/2019.11.02.093
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