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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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The activity of serratiopeptidase on oral wound healing in rabbits

Author: FAEHAA AL-MASHHADANE
Abstract: Study serratiopeptidase effects on healing of buccal mucosal wound in rabbits. Material and Method: Twenty male rabbits, divided into 2 groups; 10 untreated animals (control) and another 10 animals treated by serratiopeptidase ( 5 mg/kg orally), once a day for 10 days. Rabbits of both groups received general anesthesia (xylazine hydrochloride and ketamine hydrochloride), a standard incisions were done on oral mucosa of all rabbits, wound healing assessment was determined by histopathological, and hematological investigations. Results: statistics was used to study the differences in wound characters for study groups, Significant differences were shown between 2 groups (p< 0.001). Conclusions: Use of serratiopeptidase cannot improve and even delay healing of buccal mucosal wound in rabbits.
Keyword: serratiopeptidase, buccal wounds, healing .
DOI: https://doi.org/10.31838/ijpr/2019.11.02.088
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