Impact Factor for Five Years is 1.55 (2012 - 2016). IJPRT Re-launched from 2017, for more details visit www.ijprtonline.com

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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
ISSN
0975-2366
5 - Years Impact Factor

Year 2012 - 2016

Impact Factor: 1.55

Total Publications: 317

Total Citation: 491

Year 2011 - 2015

Impact Factor: 1.46

Total Publications: 326

Total Citation: 477

Year 2010 - 2014

Impact Factor: 1.3

Total Publications: 313

Total Citation: 407

Year 2009 - 2013

Impact Factor: 0.973

Total Publications: 293

Total Citation: 285

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January - March 6 [1] 2014

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Article Detail

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Synthesis, biological evaluation and characterization of thiazolidine-4-one derivatives as anti hyperglycemic agents

Author: DEVARAKONDA KUMAR, RAMANAYAM S K SHARMA, RAMACHANDRULA KRISHNA KUMAR, SHRIKANTH. H. HAVELE, S. V. MURAIMOHAN RAO
Abstract: The present paper has been focused on to synthesize new thiazolidin-4-one derivatives by molecular conjunction, by adopting appropriate synthetic routes. Purification of intermediates and final compounds has been done by recrystallization from suitable solvents and also by chromatographic techniques. Characterization of all the synthesized thiazolidine-4-one derivatives including those of intermediates by physical and spectral data. All the twelve derivatives of thiazoodone-4-ones were screened for anti-diabetic activity by enzymatic glucose-oxidase-peroxidase (GOD-POD) method on diabetic rats and the results are compared with standard drug Glibenclamide.
Keyword: Thiazolidin-4-one derivatives, characterization, GOD-POD method and Evaluation.
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News & Events
Impact Factor for five years is 1.55 (2012 - 2016)
Year 2011 - 2015 Impact Factor - 1.46 Total Publications - 326 Total Citations - 477
Impact Factor for five years is 1.3 (2010 - 2014)