Impact Factor for Five Years is 1.55 (2012 - 2016). IJPRT Re-launched from 2017, for more details visit www.ijprtonline.com

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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
ISSN
0975-2366
5 - Years Impact Factor

Year 2012 - 2016

Impact Factor: 1.55

Total Publications: 317

Total Citation: 491

Year 2011 - 2015

Impact Factor: 1.46

Total Publications: 326

Total Citation: 477

Year 2010 - 2014

Impact Factor: 1.3

Total Publications: 313

Total Citation: 407

Year 2009 - 2013

Impact Factor: 0.973

Total Publications: 293

Total Citation: 285

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January - March 6 [1] 2014

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Article Detail

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Formulation and Evaluation of Polymer Carrier System for Venlafaxine Hydrochloride Rapid Disintegrating Tablet

Author: PARAG BAKSHE, PROF. (DR.) VIJAY R. PATIL, PROF. (DR.) RAJESH Y. CHAUDHARI, MR. SACHIN S. RANE
Abstract: Venlafaxine Hydrochloride, a novel antidepressant which used to treat psychosis is embedded as model drug in present investigation. In study we formulated mouth dissolving tablets of model drug by polymer carrier system with direct compression method using tableting aids and evaluated. The drug polymer complex was characterized for physical description, Bulk Density, Tapped Density, Compressibility Index, Hausner Ratio, Angle of Repose then subjected to FTIR studies and in vitro drug release studies. It was found that drug polymer complex P4 containing super disintegrant showed release within few seconds. The prepared tablets were evaluated for weight, thickness, hardness, friability, disintegration and drug dissolution of about 98 % achieved within 180 seconds. The prepared tablets stability tested at 40°C with Relative Humidity of 75 % for 3 months and they found to be stable in evaluation parameters.
Keyword: Venlafaxine, Rapid disintegrating, direct compression method, polymer carrier system
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Scopus (Elsevier)
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Ulrich's International Periodical Dictionary
Indian Science Abstract
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News & Events
Impact Factor for five years is 1.55 (2012 - 2016)
Year 2011 - 2015 Impact Factor - 1.46 Total Publications - 326 Total Citations - 477
Impact Factor for five years is 1.3 (2010 - 2014)