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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
ISSN
0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Antidiabetic activity of novel algal formulations (Padina tetrastromatica and Turbinariae conoides) against Streptozotocin induced diabetes in albino rats

Author: RAJESHKUMAR S, B. DIVYA, C MALARKODI
Abstract: Brown seaweeds are the major nutritional resource used in throughout the globe. In this present study, the combination of two marine brown seaweeds (Padina tetrastromatica and Turbinaria conoides) formulation is used for antidiabetic activity on streptozotocin induced toxicity in male albino rats. Diabetic rats were treated with a 250 mg/kg of body weight and 500 mg/kg of body weight aqueous formulation and biochemical parameters such as blood glucose, insulin, total protein and total cholesterol. The histopatholgic changes in pancreatic cell morphology were analysed using haematoxylin and eosin strain by microscope. The results of the present investigation validate the antidiabetic activity of the algal formulation (P. tetrastromatica and T. conoides) in ancient pharmaceutical agents and contribute towards the developments of modern treatment opportunity based on natural products.
Keyword: Antidiabetic activity; marine algae; Padina tetrastromatica; Turbinaria conoides; algal formulations;
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0.12
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