Impact Factor for Five Years is 1.55 (2012 - 2016). 22nd National Convention of Society of Pharmacognosy & International Conference. For more details visit https://ncsp.ganpatuniversity.ac.in/index.php

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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence

IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

ISSN
0975-2366
5 - Years Impact Factor

Year 2012 - 2016

Impact Factor: 1.55

Total Publications: 317

Total Citation: 491

Year 2011 - 2015

Impact Factor: 1.46

Total Publications: 326

Total Citation: 477

Year 2010 - 2014

Impact Factor: 1.3

Total Publications: 313

Total Citation: 407

Year 2009 - 2013

Impact Factor: 0.973

Total Publications: 293

Total Citation: 285

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Article In Press
Antioxidant activity and total phenolic content in 15 commonly used cucurbits in Tarai region of Kumaun, Uttarakhand.
Analytical Method Development and Validation for the Simultaneous Estimation of Ambroxol Hydrochloride and Guaiphenesin in Syrup Dosage form by RP-HPLC
Role of NMDA receptor antagonist in ethanol withdrawal syndrome
STABILITY INDICATING LC-MS/MS METHOD FOR QUANTIFICATION OF IBRUTINIB IN HUMAN PLASMA
A review on drug: Amantadine
Chemopreventive and antioxidative activity of Carissa carandas extract against chemical induced skin tumorigenesis in mice
ROLE OF AMIODARONE IN ACUTE MYOCARDIAL INFARACTION INDUCED VENTRICULAR TACHYCARDIA IN PATIENTS WITH LEFT ANTERIOR DESCENDING ARTERY INVOLVEMENT
Extraction optimisation, fractionation, standardisation, in vitro antioxidant and anticholinesterase activity of fractions of Indian Propolis
Development of validated stability-indicating analytical method for simultaneous estimation of Atenolol and Hydrochlorothiazide in pharmaceutical combined dosage form by High Performance Thin Layer Chromatography.
Lung Cancer in Lifelong Never Smokers-Short Review
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IJPRT ISSUE

January - March 6 [1] 2014

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Article Detail

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3D-QSAR Studies CoMFA/CoMSIA and in silico docking studies on diverse structural classes of HIV-1 integrase inhibitors

Author: NEELAMMA MANTRI, ANUSHA VARANASI, VIJAYA LAKSHMI LOKIREVU, SESHAGIRI BANDI, AYUB SHAIK
Abstract: Combination of structure-based and ligand based drug design categeory, used to build 3D-QSAR model for a series of 37 experimentally known phthalimide derivatives. Comparative molecular field analysis (COMFA) and comparative molecular similarity indices analysis (COMSIA) methodologies were applied to a training set of 28 molecules and a test set of 9 molecules. The best statistical result of COMFA model gave r2 (non-cross validated square of r2= 0.984 and q2= 0.662, while for COMSIA r2= 0.967 and q2= 0.640. Predictive capability of these models supported by docking studies, produced better docking scores and binding affinity to the specified target HIV1 Integrase (1BLU).
Keyword: 3D-QSAR, COMFA, COMSIA, docking, phthalimide derivatives
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22nd National Convention of Society of Pharmacognosy & International Conference. For more details visit https://ncsp.ganpatuniversity.ac.in
Impact Factor for five years is 1.55 (2012 - 2016)
Year 2011 - 2015 Impact Factor - 1.46 Total Publications - 326 Total Citations - 477
Impact Factor for five years is 1.3 (2010 - 2014)