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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
ISSN
0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Activity enhancement of Neem (Azadirachta indica) based repellent cream using biodegradable botanical synergist

Author: DR. SHARMA, ARPANA KUMARI, NUSRAT SIDDHIQA, DR. RANJU SHARMA (CORRESPONDING AUTHOR), DR. P.K.PATANJALI
Abstract: We prepare a formulation using four different concentrations of lemon grass and neem seed oil using botanical plant extract as a synergist. Stability and efficacy of each cream formulation were observed against Ades agypti. Result showed that the efficacy of cream formulation were significantly increased by 45% with n without botanical synergist. Even the cream formulation with higher concentration of neem seed oil i.e. 10% v/w was observed to be less effective. It also stabilize the active ingredient of lemon grass and neem seed oil to give more protection time against mosquitoes. Thus the result suggests that botanical synergist increase the bio-efficacy and stability of lemon grass and neem seed oil and provides a stable, eco-friendly and economically efficient formulation in the form of cream which can be an efficient substitute for toxic mosquito’s repellents.
Keyword: Neem seed oil, Lemon grass oil, Botanical synergist, Cream formulation, Aedes aegypti, Repellency, Mortality
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