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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
ISSN
0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Synthesis and Biological Evaluation of Some Novel Nitrogen Containing Small Heterocyclic Derivatives

Author: GAGAN KAUR, DR. MANU SHARMA
Abstract: Nitrogen and sulfur containing heterocyclic rings are have emerged as important system in the hands of medicinal chemist due to their wide spectrum of activities. Novel 1,3,4-thiadiazol-2-yl)-benzenesulfonamides were synthesized and characterized by spectroscopic techniques. Further evaluation was done for anti-inflammatory activity by carageenan induced paw edema method and analgesic activities by acetic acid writhing and tail immersion tests in vivo. Almost all the compounds demonstrated good to significant activity profile.
Keyword: Heterocyclic compounds, synthesis, analgesic, NSAIDS, anti-inflammatory agents.
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0.12
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