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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
ISSN
0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Isolation and Characterisation of Natural Mucillage from Cucumis melo L.

Author: DR.E.VADIVEL , SWATI SUBASH NAIK
Abstract: Mucilages are found as common ingredients in cosmetic, pharmaceutical, food and non-food industries due to their low cost compared to the synthetic polymers. The synthetic polymer such as excipients suffer from many disadvantages such as high cost, toxicity, non-biodegradability and environmental pollution caused during their synthesis. In the present study mucilage was isolated from the fruits of Cucumis melo (Muskmelon). The mucilage was extracted using distilled water and isolated by two methods such as precipitation with ethanol and acetone. The isolated mucilage was characterized by physicochemical properties such as solubility, pH, swelling index, Loss on drying, preliminary phytochemical studies and FTIR. The micromeritic properties such as bulk and tapped densities, Carr’s index, Hausner’s ratio and angle of response were also evaluated. The results show that only carbohydrates and amino acids were present in isolated mucilage. These tests indicate the purity of the mucilage. Extracted mucilage was soluble in warm water while insoluble in organic solvents. This showed that this can be safely used in dosage form without causing any adverse effect.
Keyword: : Cucumis melo , Muskmelon, Isolation, Mucilage
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