IJPR  articles are Indexed in SCOPUSClick Here     Impact Factor for Five Years is 0.13 (2013 - 2018).    

logo

INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence

IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
ISSN
0975-2366
Current Issue
Article In Press
No Data found.
ADOBE READER

(Require Adobe Acrobat Reader to open, If you don't have Adobe Acrobat Reader)

Index Page 1
Click here to Download
IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

Click to download
 

Article Detail

Label
Label
Anti-convulsion activity of leaf of Trema orientalis.

Author: UPLOADED BY-ADMIN, PANCHAL HITEKSHA S., MASTER STAVAN M., SHAH URVASHI D., SALUJA AJAY K., DHOLWANI KISHOR K.
Abstract: In vitro anti-convulsion activity of Trema orientalis at varying doses of suspension of dried leaves were tested using Maximum Electroshock induced seizures model and Pentylenetetrazole induced convulsions model. The anti-convulsion activity of Trema orientalis methanol extract of leaves shows tonic flexion (7.30±1.15 sec) and tonic extension (10.38±1.15 sec) in Maximum Electroshock induced seizures model and onset time (125 sec) in Pentylenetetrazole induced convulsions model. model which gives more anti-convulsion effect as compared to aqueous extract of leaves which shows tonic flexion (6.12±1.04 sec) and tonic extension (9.88±1.2 sec) in Maximum Electroshock induced seizures model and onset time (117 sec) in Pentylenetetrazole induced convulsions model of epilepsy but as compared to standard, methanol and aqueous extract gives less anti-convulsion effect. Phytochemical investigation of Trema orientalis extracts shows presence of tannins and Phenolic compounds, fixed oils, fats, phytosterols, flavonoids which has been responsible for anti-convulsion activity.
Keyword: Trema orientalis, Electroshock induced seizures model, Pentylenetetrazole (Metrazol) induced convulsionsmodel, Anti-convulsion activity
Download: Request For Article
 












ONLINE SUBMISSION
USER LOGIN


Username
Password
Login | Register
News & Events

Terms and Conditions
Disclaimer
Refund Policy
Instrucations for Subscribers
Privacy Policy

Copyrights Form

0.12
2018CiteScore
 
8th percentile
Powered by  Scopus
Google Scholar

hit counters free